Hypertension, defined as resting blood pressure of ≥140/90,impacts over 29% of the adult American population and is a leading cause of renal disease, heart attack, and stroke (Gropper, Smith, and Carr, 2018). Sodium (Na) was one of the first micronutrients mechanistically linked with hypertension, and has since become a commonly understood factor in risk and […]
Read MorePhospholipase enzyme 2 (PLA2) represents a group of enzymes found in the plasma. In particular, the primary enzymes behind phospholipid hydrolyzing processes is found amongst a sub-group known as secretory PLA2 (SPLA2) and have been associated with atherosclerosis (Garces et al., 2010). As such, the following will explore said enzymes in greater detail, other biomarkers […]
Read MoreVitamin K, a fat-soluble micronutrient, is found naturally in two forms to include phylloquinone (K1) and menaquinone (K2) (Gropper, Smith, & Carr, 2018). Said vitamin is widely recognized for its role in the synthesis of γ-carboxyglutamic acid (GLA); a residue necessary for blood clotting (Gropper et al., 2018). However, a lesser known function of vitamin […]
Read MorePyridoxine (B6), is a micronutrient which serves as a coenzyme in over 100 enzymes (Grooper, Smith, & Carr, 2018). Furthermore, its primary role is found in the metabolism of glucose, carnitine, neurotransmitters, heme, nucleic acids, sphingolipids, and amino acids (Gropper et al., 2018). Considering B6’s integral role as a coenzyme and its involvement in energy/neurotransmitter […]
Read MoreB9, also known as folate, is a water-soluble micronutrient central to health and homeostasis (Sanvisens et al., 2017). Functions include the metabolism of nutrients such as choline, amino acids, pyrimidines, purines, DNA synthesis/repair, and cell division (Gropper, Smith, & Carr, 2018). As such, deficiencies in folate can lead to disruptions in said functions. As a […]
Read MoreLow grade chronic inflammation (LGCI) is a condition characterized by a persistent presence of inflammatory processes, that eventually manifests as tissue damage (Nasef, Mehta, & Ferguson, 2017). LGCI is also implicated with several diseases to include autoimmune disease, cardiovascular disease, stroke, and diabetes (Kenney, Wilmore, & Costill, 2012; Nasef et al., 2017). Essentially, mitigating the inflammatory […]
Read MoreThe human body communicates, interacts, and coordinates with itself and the external environment through a dense network of electrochemical conduits, colloquially known as the nerves or nervous system (NS) (Kenney, Wilmore, & Costill, 2012). Virtually all tissues, organs, motor, and sensory systems are fully integrated with the NS; like a conductor in an orchestra, the […]
Read MoreHumans have survived in unique and diverse environments, to include equally unique and diverse foods and dietary habits. However, it is also true that particular nutritional proclivities have the potential to induce unfavorable physiological consequences that inhibit optimal health and longevity. In the following sections, I would like to explore vegan/vegetarian diets, strengths, limitations, and […]
Read MoreThe heart is a muscle (cardiac muscle) critical to sustaining life and homeostasis. Such an organ serves as a pump, which propels blood towards the lungs and other tissues via associated vasculature (Reisner & Reisner, 2017). Cardiac muscle is designed to work in almost near perpetuity; other muscles (i.e., skeletal) are not always required to […]
Read MoreCoQ10 is a nutrient whose production tends to become down-regulated by two main sources: genetic mutations involved in its synthesis (a primary deficiency) and statins, which inhibit an enzyme (hydroxymethylglutaryl coenzyme A) involved in the development of CoQ10 (considered a secondary deficiency) (Potgieter, Pretorius, & Pepper, 2013). Secondary deficiency is a common side-affect amongst individuals on […]
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